Conflicts of Interest

Hidehisa Saeki, Teppei Hagino, Sei-ichiro Motegi, and Naoko Kanda received lecture fees from Eli Lilly and LEO Pharma. Akihiko Uchiyama and Eita Fujimoto have no conflicts of interest that are directly relevant to the content of this article.

Consent to Participate

Informed consent was obtained from all subjects involved in the study.

Consent for Publication

Not applicable.

Ethics Approval

This study was conducted in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of Gunma University, Nippon Medical School Chiba Hokusoh Hospital, and Nippon Medical School (ethics approval number: R-2024-160).

Availability of Data and Material

The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.

Code Availability

Not applicable.

Authors’ Contributions

All authors contributed significantly to the article and agree with its content. TH conceptualized the study and organized the manuscript. NK supervised the study. AU, HS, SM, and EF revised the manuscript. All authors read and approved the final version of the manuscript.