Abad-Casintahan F, Chow SKW, Goh CL, Kubba R, Hayashi N, Noppakun N, et al. Frequency and characteristics of acne-related post-inflammatory hyperpigmentation. J Dermatol. 2016;43(7):826–8. https://doi.org/10.1111/1346-8138.13263.

Article  PubMed  Google Scholar 

Elbuluk N, Grimes P, Chien A, Hamzavi I, Alexis A, Taylor S, et al. The pathogenesis and management of acne-induced post-inflammatory hyperpigmentation. Am J Clin Dermatol. 2021;22(6):829–36. https://doi.org/10.1007/s40257-021-00633-4.

Article  PubMed  Google Scholar 

Abanmi A, Al-Enezi M, Al Hammadi A, Galadari I, Kibbi AG, Zimmo S. Survey of acne-related post-inflammatory hyperpigmentation in the Middle East. J Dermatolog Treat. 2019;30(6):578–81. https://doi.org/10.1080/09546634.2018.1542807.

Article  CAS  PubMed  Google Scholar 

Davis EC, Callender VD. Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color. J Clin Aesthet Dermatol. 2010;3(7):20–31.

PubMed  PubMed Central  Google Scholar 

Tan MG, Kim WB, Jo CE, Nabieva K, Kirshen C, Ortiz AE. Topical treatment for postinflammatory hyperpigmentation: a systematic review. J Dermatolog Treat. 2022;33(5):2518–26. https://doi.org/10.1080/09546634.2021.1981814.

Article  CAS  PubMed  Google Scholar 

Alexis AF, Sergay AB, Taylor SC. Common dermatologic disorders in skin of color: a comparative practice survey. Cutis. 2007;80(5):387–94.

PubMed  Google Scholar 

Layton A, Alexis A, Baldwin H, Beissert S, Bettoli V, Del Rosso J, et al. Identifying gaps and providing recommendations to address shortcomings in the investigation of acne sequelae by the Personalising Acne: Consensus of Experts Panel. JAAD Int. 2021;5:41–8. https://doi.org/10.1016/j.jdin.2021.06.006.

Article  PubMed  PubMed Central  Google Scholar 

Davis EC, Callender VD. A review of acne in ethnic skin: pathogenesis, clinical manifestations, and management strategies. J Clin Aesthet Dermatol. 2010;3(4):24–38.

PubMed  PubMed Central  Google Scholar 

Alexis A, Del Rosso JQ, Forman S, Martorell A, Browning J, Laquer V, et al. Importance of treating acne sequelae in skin of color: 6-month phase IV study of trifarotene with an appropriate skincare routine including UV protection in acne-induced post-inflammatory hyperpigmentation. Int J Dermatol. 2024;63(6):806–15. https://doi.org/10.1111/ijd.17189.

Article  CAS  PubMed  Google Scholar 

Arsiwala S, Desai S. Fractional carbon dioxide laser: optimizing treatment outcomes for pigmented atrophic acne scars in skin of color. J Cutan Aesthet Surg. 2019;12(2):85–94. https://doi.org/10.4103/JCAS.JCAS_171_18.

Article  PubMed  PubMed Central  Google Scholar 

Silpa-Archa N, Kohli I, Chaowattanapanit S, Lim HW, Hamzavi I. Postinflammatory hyperpigmentation: a comprehensive overview: epidemiology, pathogenesis, clinical presentation, and noninvasive assessment technique. J Am Acad Dermatol. 2017;77(4):591–605. https://doi.org/10.1016/j.jaad.2017.01.035.

Article  PubMed  Google Scholar 

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, et al. Photoprotection according to skin phototype and dermatoses: practical recommendations from an expert panel. J Eur Acad Dermatol Venereol. 2021;35(7):1460–9. https://doi.org/10.1111/jdv.17242.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Burns EM, Ahmed H, Isedeh PN, Kohli I, Van Der Pol W, Shaheen A, et al. Ultraviolet radiation, both UVA and UVB, influences the composition of the skin microbiome. Exp Dermatol. 2019;28(2):136–41. https://doi.org/10.1111/exd.13854.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Poli F. Acne on pigmented skin. Int J Dermatol. 2007;46(Suppl. 1):39–41. https://doi.org/10.1111/j.1365-4632.2007.03463.x.

Article  PubMed  Google Scholar 

Goh CL, Noppakun N, Micali G, Azizan NZ, Boonchai W, Chan Y, et al. Meeting the challenges of acne treatment in Asian patients: a review of the role of dermocosmetics as adjunctive therapy. J Cutan Aesthet Surg. 2016;9(2):85–92. https://doi.org/10.4103/0974-2077.184043.

Article  PubMed  PubMed Central  Google Scholar 

Features C. A review of the epidemiology, clinical features, and treatment options in skin of color. Year study population prevalence rank. 2010;3(7).

Al-Qarqaz F, Bodoor K, Baba A, Al-Yousef A, Muhaidat J, Alshiyab D. Post-acne hyperpigmentation: evaluation of risk factors and the use of artificial neural network as a predictive classifier. Dermatol Rep. 2021;13(3):8223. https://doi.org/10.4081/dr.2021.8223.

Article  Google Scholar 

Schuster B, Gallinger J, Philipp-Dormston WG, Vasel M, Layton AM. Less confident, successful and happy: patients with post-acne hyperpigmentation are stigmatized. Br J Dermatol. 2023;188(5):682–4. https://doi.org/10.1093/bjd/ljad026.

Article  PubMed  Google Scholar 

Savory SA, Agim NG, Mao R, Peter S, Wang C, Maldonado G, et al. Reliability assessment and validation of the postacne hyperpigmentation index (PAHPI), a new instrument to measure postinflammatory hyperpigmentation from acne vulgaris. J Am Acad Dermatol. 2014;70(1):108–14. https://doi.org/10.1016/j.jaad.2013.09.017.

Article  PubMed  Google Scholar 

Auffret N, Leccia MT, Ballanger F, Claudel JP, Dahan S, Dréno B. Acne-induced post-inflammatory hyperpigmentation: from grading to treatment. Acta Derm Venereol. 2025;105:1–9. https://doi.org/10.2340/actadv.v105.42925.

Article  CAS  Google Scholar 

Kesty CE, Kesty KR. The Kesty Hyperpigmentation Scale: a study to validate a new tool for assessing facial hyperpigmentation. J Cosmet Dermatol. 2025;24(4):e70055. https://doi.org/10.1111/jocd.70055.

Article  PubMed  PubMed Central  Google Scholar 

Dabbas D. Comparison of MELASQOL and DLQI in female patients suffering from melasma and nonmelasma facial melanosis: a cross-sectional study. Pigment Int. 2023;10(2):93–96.

Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI): a simple practical measure for routine clinical use. Clin Exp Dermatol. 1994;19(3):210–6. https://doi.org/10.1111/j.1365-2230.1994.tb01167.x.

Article  CAS  PubMed  Google Scholar 

Chren MM, Lasek RJ, Flocke SA, Zyzanski SJ. Improved discriminative and evaluative capability of a refined version of Skindex, a quality-of-life instrument for patients with skin diseases. Arch Dermatol. 1997;133(11):1433–40.

Article  CAS  PubMed  Google Scholar 

Yoshimura K, Tsukamoto K, Okazaki M, Virador VM, Lei TC, Suzuki Y, et al. Effects of all-trans retinoic acid on melanogenesis in pigmented skin equivalents and monolayer culture of melanocytes. J Dermatol Sci. 2001;27(Suppl. 1):S68-75. https://doi.org/10.1016/s0923-1811(01)00116-5.

Article  CAS  PubMed  Google Scholar 

Elias PM. Epidermal effects of retinoids: supramolecular observations and clinical implications. J Am Acad Dermatol. 1986;15(4 Pt 2):797–809. https://doi.org/10.1016/s0190-9622(86)70236-3.

Article  CAS  PubMed  Google Scholar 

Kang HY, Valerio L, Bahadoran P, Ortonne JP. The role of topical retinoids in the treatment of pigmentary disorders: an evidence-based review. Am J Clin Dermatol. 2009;10(4):251–60. https://doi.org/10.2165/00128071-200910040-00005.

Article  PubMed  Google Scholar 

Aubert J, Piwnica D, Bertino B, Blanchet-Réthoré S, Carlavan I, Déret S, et al. Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-γ agonist trifarotene. Br J Dermatol. 2018;179(2):442–56. https://doi.org/10.1111/bjd.16719.

Article  CAS  PubMed  Google Scholar 

Issa N, Alexis A, Baldwin H, Hamzavi I, Hebert A, Kwong P, et al. Recommendations to improve outcomes in acne and acne sequelae: a focus on trifarotene and other retinoids. Dermatol Ther. 2025;15(3):563–77. https://doi.org/10.1007/s13555-025-01344-y.

Article  Google Scholar 

Bulengo-Ransby SM, Griffiths CE, Kimbrough-Green CK, Finkel LJ, Hamilton TA, Ellis CN, et al. Topical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in Black patients. N Engl J Med. 1993;328(20):1438–43. https://doi.org/10.1056/NEJM199305203282002.

Article  CAS  PubMed  Google Scholar 

Jacyk WK, Mpofu P. Adapalene gel 0.1% for topical treatment of acne vulgaris in African patients. Cutis. 2001;68(4 Suppl.):48–54.

CAS  PubMed  Google Scholar 

Grimes P, Callender