Bedford MT, van Helden PD. Hypomethylation of DNA in pathological conditions of the human prostate. Cancer Res. 1987;47:5274–6.

CAS  PubMed  Google Scholar 

Choi JY, James SR, Link PA, et al. Association between global DNA hypomethylation in leukocytes and risk of breast cancer. Carcinogenesis. 2009;30:1889–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Daskalos A, Nikolaidis G, Xinarianos G, Savvari P, Cassidy A, Zakopoulou R, Kotsinas A, Gorgoulis V, Field JK, Liloglou T. Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer. Int J Cancer. 2009;124(1):81–7.

Article  CAS  PubMed  Google Scholar 

Feinberg AP, Gehrke CW, Kuo KC, Ehrlich M. Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res. 1988;48:1159–61.

CAS  PubMed  Google Scholar 

Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer. 2004;4:143–53. https://doi.org/10.1038/nrc1279.

Article  CAS  PubMed  Google Scholar 

Gama-Sosa MA, Slagel VA, Trewyn RW, Oxenhandler R, Kuo KC, Gehrke CW, Ehrlich M. The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res. 1983;11:6883–94. https://doi.org/10.1093/nar/11.19.6883.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Herman JG. Hypermethylation of tumor suppressor genes in cancer. Semin Cancer Biol. 1999;9:359–67. https://doi.org/10.1006/scbi.1999.0138.

Article  CAS  PubMed  Google Scholar 

Hou L, Wang H, Sartori S, et al. Blood leukocyte DNA hypomethylation and gastric cancer risk in a high-risk polish population. Int J Cancer. 2010;127:1866–74.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang WY, Su LJ, Hayes RB, et al. Prospective study of genomic hypomethylation of leukocyte DNA and colorectal cancer risk. Cancer Epidemiol Biomark Prev. 2012;21:2014–21.

Article  CAS  Google Scholar 

India State-level Disease Burden Initiative Cancer Collaborators. The burden of cancers and their variations across the states of India: the global burden of disease study 1990–2016. Lancet Oncol. 2018;19:1289–306.

Article  Google Scholar 

Kawano H, Saeki H, Kitao H, Tsuda Y, Otsu H, Ando K, Ito S, Egashira A, Oki E, Morita M, Oda Y, Maehara Y. Chromosomal instability associated with global DNA hypomethylation is associated with the initiation and progression of esophageal squamous cell carcinoma. Ann Surg Oncol. 2014;21(Suppl 4):S696-702.

Article  PubMed  Google Scholar 

Lim U, Song MA. Dietary and lifestyle factors of DNA methylation. Methods Mol Biol. 2012;863:359–76.

Article  CAS  PubMed  Google Scholar 

Moore L, Le T, Fan G. DNA methylation and its basic function. Neuro Psycho Pharmacol. 2013;38:23–38. https://doi.org/10.1038/npp.2012.112.

Article  CAS  Google Scholar 

Rauh-Hain JA, Krivak TC, Del Carmen MG, Olawaiye AB. Ovarian cancer screening and early detection in the general population. Rev Obstet Gynecol. 2011;4(1):15–21.

PubMed  PubMed Central  Google Scholar 

Ruiz-Hernandez A, Kuo CC, Rentero-Garrido P, et al. Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence. Clin Epigenetics. 2015;7:55.

Article  PubMed  PubMed Central  Google Scholar 

Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis. 2010;31(1):27–36. https://doi.org/10.1093/carcin/bgp220.

Article  CAS  PubMed  Google Scholar 

Teschendorff AE, Menon U, Gentry-Maharaj A, et al. An epigenetic signature in peripheral blood predicts active ovarian cancer. PLoS One. 2009;4: e8274. https://doi.org/10.1371/journal.pone.0008274.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang W, Klinkebiel D, Barger CJ, Pandey S, Guda C, Miller A, Akers SN, Odunsi K, Karpf AR. Global DNA hypomethylation in epithelial ovarian cancer: passive demethylation and association with genomic instability. Cancers (Basel). 2020;12(3):764.

Article  CAS  PubMed  Google Scholar