McDonagh TA, Metra M, Adamo M et al (2021) 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42:3599–3726

Article  CAS  PubMed  Google Scholar 

Mele D, Andrade A, Bettencourt P et al (2020) From left ventricular ejection fraction to cardiac hemodynamics: role of echocardiography in evaluating patients with heart failure. Heart Fail Rev 25:217–230

Article  PubMed  Google Scholar 

Palazzuoli A, Correale M, Iacoviello M, Gronda E (2023) Does the Measurement of ejection fraction still make sense in the HFpEF framework? What recent trials suggest. J Clin Med 12:693

Article  PubMed  PubMed Central  Google Scholar 

Palazzuoli A, Ruocco G, Valente S et al (2022) Non-invasive assessment of acute heart failure by Stevenson classification: does echocardiographic examination recognize different phenotypes? Front Cardiovasc Med 9. https://doi.org/10.3389/FCVM.2022.911578

Dini FL, Pestelli G, Pugliese NR et al (2022) Combining echo-derived haemodynamic phenotypes and myocardial strain for risk stratification of chronic heart failure with reduced ejection fraction. Eur Hear J - Cardiovasc Imaging. https://doi.org/10.1093/ehjci/jeac127

Article  Google Scholar 

Dini FL, Carluccio E, Bitto R et al (2022) Echocardiographically defined haemodynamic categorization predicts prognosis in ambulatory heart failure patients treated with sacubitril/valsartan. ESC Hear Fail 9:1107–1117. https://doi.org/10.1002/ehf2.13779

Article  Google Scholar 

Chubuchny V, Pugliese NR, Taddei C et al (2021) A novel echocardiographic method for estimation of pulmonary artery wedge pressure and pulmonary vascular resistance. ESC Hear Fail 8:1216–1229. https://doi.org/10.1002/ehf2.13183

Article  Google Scholar 

Forrester JS, Diamond G, Chatterjee K, Swan HJC (1976) Medical therapy of acute myocardial infarction by application of hemodynamic subsets. N Engl J Med 295:1404–1413. https://doi.org/10.1056/nejm197612162952505

Article  CAS  PubMed  Google Scholar 

Steimle AE, Stevenson LW, Chelimsky-Fallick C et al (1997) Sustained hemodynamic efficacy of therapy tailored to reduce filling pressures in survivors with advanced heart failure. Circulation 96:1165–1172. https://doi.org/10.1161/01.CIR.96.4.1165

Article  CAS  PubMed  Google Scholar 

Stevenson LW, Tillisch JH, Hamilton M et al (1990) Importance of hemodynamic response to therapy in predicting survival with ejection fraction ≤ 20% secondary to ischemic or nonischemic dilated cardiomyopathy. Am J Cardiol 66:1348–1354. https://doi.org/10.1016/0002-9149(90)91166-4

Article  CAS  PubMed  Google Scholar 

Drazner MH, Stevenson LW (2019) Relief and prevention of congestion in heart failure enhance quality and length of life. Circulation 140:1380–1382

Article  PubMed  Google Scholar 

Pugliese NR, Pellicori P, Filidei F et al (2023) The incremental value of multi-organ assessment of congestion using ultrasound in outpatients with heart failure. Eur Hear J - Cardiovasc Imaging. https://doi.org/10.1093/ehjci/jeac254

Article  Google Scholar 

Lindenfeld JA, Zile MR, Desai AS et al (2021) Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial. Lancet 398:991–1001. https://doi.org/10.1016/S0140-6736(21)01754-2

Article  CAS  PubMed  Google Scholar 

Kim KH, Jentzer JC, Wiley BM et al (2021) Diamond-Forrester classification using echocardiography haemodynamic assessment in cardiac intensive care unit patients. ESC Hear Fail. https://doi.org/10.1002/ehf2.13527

Article  Google Scholar 

Temporelli PL, Corrà U, Imparato A et al (1998) Reversible restrictive left ventricular diastolic filling with optimized oral therapy predicts a more favorable prognosis in patients with chronic heart failure. J Am Coll Cardiol 31:1591–1597. https://doi.org/10.1016/S0735-1097(98)00165-X

Article  CAS  PubMed  Google Scholar 

Traversi E, Pozzoli M, Cioffi G et al (1996) Mitral flow velocity changes after 6 months of optimized therapy provide important hemodynamic and prognostic information in patients with chronic heart failure. Am Heart J 132:809–819. https://doi.org/10.1016/S0002-8703(96)90316-6

Article  CAS  PubMed  Google Scholar 

Nagueh SF, Smiseth OA, Appleton CP et al (2016) Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 29:277–314. https://doi.org/10.1016/j.echo.2016.01.011

Article  PubMed  Google Scholar 

Palazzuoli A, Ruocco G, Beltrami M et al (2018) Combined use of lung ultrasound, B-type natriuretic peptide, and echocardiography for outcome prediction in patients with acute HFrEF and HFpEF. Clin Res Cardiol 107:586–596. https://doi.org/10.1007/s00392-018-1221-7

Article  CAS  PubMed  Google Scholar 

Pugliese NR, Fabiani I, Conte L et al (2020) Persistent congestion, renal dysfunction and inflammatory cytokines in acute heart failure: a prognosis study. J Cardiovasc Med 21:494–502. https://doi.org/10.2459/JCM.0000000000000974

Article  CAS  Google Scholar 

Gargani L, Pugliese NR, Frassi F et al (2021) Prognostic value of lung ultrasound in patients hospitalized for heart disease irrespective of symptoms and ejection fraction. ESC Hear Fail 8:2660–2669. https://doi.org/10.1002/ehf2.13206

Article  Google Scholar 

Dini FL, Traversi E, Franchini M et al (2003) Contrast-enhanced Doppler hemodynamics for noninvasive assessment of patients with chronic heart failure and left ventricular systolic dysfunction. J Am Soc Echocardiogr 16:124–131. https://doi.org/10.1067/mje.2003.8

Article  PubMed  Google Scholar 

Potter E, Marwick TH (2018) Assessment of left ventricular function by echocardiography: the case for routinely adding global longitudinal strain to ejection fraction. JACC Cardiovasc Imaging 11:260–274. https://doi.org/10.1016/j.jcmg.2017.11.017

Article  PubMed  Google Scholar 

Carluccio E, Dini FL, Biagioli P et al (2013) The “echo heart failure score”: an echocardiographic risk prediction score of mortality in systolic heart failure. Eur J Heart Fail 15:868–876. https://doi.org/10.1093/eurjhf/hft038

Article  PubMed  Google Scholar 

Dini FL, Ballo P, Pugliese NR et al (2022) Improved diastolic dysfunction is associated with higher forward flow and better prognosis in chronic heart failure. Int J Cardiovasc Imaging 38:727–737. https://doi.org/10.1007/s10554-021-02457-z

Article  Google Scholar 

Baudry G, Coutance G, Dorent R et al (2022) Prognosis value of Forrester’s classification in advanced heart failure patients awaiting heart transplantation. ESC Hear Fail 9:3287–3297. https://doi.org/10.1002/ehf2.14037

Article  Google Scholar 

Pugliese NR, Fabiani I, Mandoli GE et al (2019) Echo-derived peak cardiac power output-to-left ventricular mass with cardiopulmonary exercise testing predicts outcome in patients with heart failure and depressed systolic function. Eur Heart J Cardiovasc Imaging 20:700–708. https://doi.org/10.1093/ehjci/jey172

Article  PubMed  Google Scholar 

St. John Sutton M, Linde C, Gold MR, et al (2017) Left ventricular architecture, long-term reverse remodeling, and clinical outcome in mild heart failure with cardiac resynchronization: results from the REVERSE Trial. JACC Hear Fail 5:169–178. https://doi.org/10.1016/j.jchf.2016.11.012

Article  Google Scholar 

Tobushi T, Nakano M, Hosokawa K et al (2017) Improved diastolic function is associated with higher cardiac output in patients with heart failure irrespective of left ventricular ejection fraction. J Am Heart Assoc 6:1–7. https://doi.org/10.1161/JAHA.116.003389

Article  Google Scholar 

Dini FL, Carluccio E, Montecucco F et al (2017) Combining echo and natriuretic peptides to guide heart failure care in the outpatient setting: a position paper. Eur J Clin Invest 47:e12846

Article  Google Scholar 

Núñez J, de la Espriella R, Rossignol P et al (2022) Congestion in heart failure: a circulating biomarker-based perspective. A review from the Biomarkers Working Group of the Heart Failure Association, European Society of Cardiology. Eur J Heart Fail. https://doi.org/10.1002/ejhf.2664

von Lueder TG, Kotecha D, Atar D, Hopper I (2017) Neurohormonal blockade in heart failure. Card Fail Rev 03:19. https://doi.org/10.15420/cfr.2016:22:2

Pugliese NR, Masi S, Taddei S (2020) The renin-angiotensin-aldosterone system: a crossroad from arterial hypertension to heart failure. Heart Fail Rev 25:31–42

Article  CAS  PubMed  Google Scholar 

Tsutsui H, Albert NM, Coats AJS et al (2023) Natriuretic peptides: role in the diagnosis and management of heart failure: a scientific statement from the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society. Eur J Heart Fail 25:616–631

Article  CAS  PubMed  Google Scholar 

Myhre PL, Prescott MF, Murphy SP et al (2022) Early B-type natriuretic peptide change in HFrEF patients treated with sacubitril/valsartan: a pooled analysis of EVALUATE-HF and PROVE-HF. JACC Hear Fail 10:119–128. https://doi.org/10.1016/j.jchf.2021.09.007

Article  Google Scholar 

Sullivan RD, Mehta RM, Tripathi R, Reed GL, Gladysheva IP (2019) Renin activity in heart failure with reduced systolic function-new insights. Int J Mol Sci 20(13):3182. https://doi.org/10.3390/ijms20133182. PMID: 31261774; PMCID: PMC6651297

McLellan J, Bankhead CR, Oke JL et al (2020) Natriuretic peptide-guided treatment for heart failure: a systematic review and meta-analysis. BMJ Evidence-Based Med 25:33–37

Article  Google Scholar 

Lee KK, Doudesis D, Anwar M et al (2022) Development and validation of a decision support tool for the diagnosis of acute heart failure: systematic review, meta-analysis, and modelling study. BMJ 377:e068424. https://doi.org/10.1136/bmj-2021-068424

Bettencourt P, Chora I, Silva F et al (2021) Acute on chronic heart failure—which variations on B‐type natriuretic peptide levels? J Am Coll Emerg Physicians Open 2. https://doi.org/10.1002/emp2.12448

Maisel AS (2001) Practical approaches to treating patients with acute decompensated heart failure. J Card Fail 7:13–17. https://doi.org/10.1054/JCAF.2001.26646

Article  CAS  PubMed  Google Scholar 

Ibrahim NE, Burnett JC, Butler J et al (2020) Natriuretic peptides as inclusion criteria in clinical trials: a JACC: heart failure position paper. JACC Hear Fail 8:347–358

Article  Google Scholar 

Moura B, Aimo A, Al-Mohammad A et al (2021) Integration of imaging and circulating biomarkers in heart failure: a consensus document by the Biomarkers and Imaging Study Groups of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 23:1577–1596. https://doi.org/10.1002/ejhf.2339

Article  PubMed  Google Scholar 

Simioniuc A, Carluccio E, Ghio S et al (2016) Echo and natriuretic peptide guided therapy improves outcome and reduces worsening renal function in systolic heart failure: an observational study of 1137 outpatients. Int J Cardiol 224:416–423. https://doi.org/10.1016/j.ijcard.2016.09.034

Article  PubMed