CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis

Batrakova EV, Kim MS (2015) Using exosomes, naturally-equipped nanocarriers, for drug delivery. J Control Release 219:396–405

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen LL, Yang L (2015) Regulation of circRNA biogenesis. RNA Biol 12:381–388

Article  PubMed  PubMed Central  Google Scholar 

Cheshomi H, Matin MM (2019) Exosomes and their importance in metastasis, diagnosis, and therapy of colorectal cancer. J Cell Biochem 120:2671–2686

Article  CAS  PubMed  Google Scholar 

Clutton S (1997) The importance of oxidative stress in apoptosis. Br Med Bull 53:662–668

Article  CAS  PubMed  Google Scholar 

Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI et al (2018) Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246. Nat Commun 9:771

Article  PubMed  PubMed Central  Google Scholar 

Donnan GA, Fisher M, Macleod M, Davis SM (2008) Stroke. Lancet 371:1612–1623

Article  CAS  PubMed  Google Scholar 

Dudekula DB, Panda AC, Grammatikakis I, De S, Abdelmohsen K et al (2016) CircInteractome: a web tool for exploring circular RNAs and their interacting proteins and microRNAs. RNA Biol 13:34–42

Article  PubMed  Google Scholar 

Fuschi P, Maimone B, Gaetano C, Martelli F (2019) Noncoding RNAs in the vascular system response to oxidative stress. Antioxid Redox Signal 30:992–1010

Article  CAS  PubMed  Google Scholar 

Gianello V, Salvi V, Parola C, Moretto N, Facchinetti F et al (2019) The PDE4 inhibitor CHF6001 modulates pro-inflammatory cytokines, chemokines and Th1- and Th17-polarizing cytokines in human dendritic cells. Biochem Pharmacol 163:371–380

Article  CAS  PubMed  Google Scholar 

Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 (2019). Lancet Neurol 18:439–458

Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR et al (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J Proteome Res 8:1304–1314

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hammond SM, Bernstein E, Beach D, Hannon GJ (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404:293–296

Article  CAS  PubMed  Google Scholar 

Han B, Zhang Y, Zhang Y, Bai Y, Chen X et al (2018) Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke. Autophagy 14:1164–1184

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hansen TB, Jensen TI, Clausen BH, Bramsen JB, Finsen B et al (2013) Natural RNA circles function as efficient microRNA sponges. Nature 495:384–388

Article  CAS  PubMed  Google Scholar 

Huang G, Zang J, He L, Zhu H, Huang J et al (2021) Bioactive nanoenzyme reverses oxidative damage and endoplasmic reticulum stress in neurons under ischemic stroke. ACS Nano 16:431–452

Article  PubMed  Google Scholar 

Kalluri R, LeBleu VS (2020) The biology, function, and biomedical applications of exosomes. Science 367:eaau6977

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kannan K, Jain SK (2000) Oxidative stress and apoptosis. Pathophysiology 7:153–163

Article  CAS  PubMed  Google Scholar 

Khoshnam SE, Winlow W, Farbood Y, Moghaddam HF, Farzaneh M (2017) Emerging roles of microRNAs in ischemic stroke: as possible therapeutic agents. J Stroke 19:166–187

Article  PubMed  PubMed Central  Google Scholar 

Kong Y, Li Y, Luo Y, Zhu J, Zheng H et al (2020) circNFIB1 inhibits lymphangiogenesis and lymphatic metastasis via the miR-486-5p/PIK3R1/VEGF-C axis in pancreatic cancer. Mol Cancer 19:82

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kristensen LS, Andersen MS, Stagsted LVW, Ebbesen KK, Hansen TB et al (2019) The biogenesis, biology and characterization of circular RNAs. Nat Rev Genet 20:675–691

Article  CAS  PubMed  Google Scholar 

Li M, Ding W, Tariq MA, Chang W, Zhang X et al (2018) A circular transcript of ncx1 gene mediates ischemic myocardial injury by targeting miR-133a-3p. Theranostics 8:5855–5869

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu M, Wang Q, Shen J, Yang BB, Ding X (2019a) Circbank: a comprehensive database for circRNA with standard nomenclature. RNA Biol 16:899–905

Article  PubMed  PubMed Central  Google Scholar 

Liu Z, Yu Y, Huang Z, Kong Y, Hu X et al (2019b) CircRNA-5692 inhibits the progression of hepatocellular carcinoma by sponging miR-328-5p to enhance DAB2IP expression. Cell Death Dis 10:900

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Z, Zhou Y, Liang G, Ling Y, Tan W et al (2019c) Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p. Cell Death Dis 10:55

Article  PubMed  PubMed Central  Google Scholar 

Lu Q, Liu T, Feng H, Yang R, Zhao X et al (2019) Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN. Mol Cancer 18:111

Article  PubMed  PubMed Central  Google Scholar 

Mehta SL, Dempsey RJ, Vemuganti R (2020) Role of circular RNAs in brain development and CNS diseases. Prog Neurobiol 186:101746

Article  CAS  PubMed  PubMed Central  Google Scholar 

Oakes SA, Papa FR (2015) The role of endoplasmic reticulum stress in human pathology. Annu Rev Pathol 10:173–194

Article  CAS  PubMed  Google Scholar 

Phipps MS, Cronin CA (2020) Management of acute ischemic stroke. BMJ 368:l6983

Article  PubMed  Google Scholar 

Qian Q, Zhang J, He FP, Bao WX, Zheng TT et al (2019) Down-regulated expression of microRNA-338-5p contributes to neuropathology in Alzheimer’s disease. FASEB J 33:4404–4417

Article  CAS  PubMed  Google Scholar 

Rivas FV, Tolia NH, Song JJ, Aragon JP, Liu J et al (2005) Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol 12:340–349

Article  CAS  PubMed  Google Scholar 

Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP (2011) A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell 146:353–358

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu B, Qin Y, Li D, Cai N, Wu J et al (2020) Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway. Redox Biol 28:101342

Article  CAS  PubMed  Google Scholar 

Yang J, Hao J, Lin Y, Guo Y, Liao K et al (2022) Profile and functional prediction of plasma exosome-derived CircRNAs from acute ischemic stroke patients. Front Genet 13:810974

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang L, Han B, Zhang Z, Wang S, Bai Y et al (2020) Extracellular vesicle-mediated delivery of circular RNA SCMH1 promotes functional recovery in rodent and nonhuman primate ischemic stroke models. Circulation 142:556–574

Article  CAS  PubMed  Google Scholar 

Yi X, Fang Q, Li L (2020) MicroRNA-338-5p alleviates cerebral ischemia/reperfusion injury by targeting connective tissue growth factor through the adenosine 5’-monophosphate-activated protein kinase/mammalian target of rapamycin signaling pathway. NeuroReport 31:256–264

Article  CAS  PubMed  Google Scholar 

Zhang A, Bai Z, Yi W, Hu Z, Hao J (2021) Overexpression of miR-338-5p in exosomes derived from mesenchymal stromal cells provides neuroprotective effects by the Cnr1/Rap1/Akt pathway after spinal cord injury in rats. Neurosci Lett 761:136124

Article  CAS  PubMed  Google Scholar 

Zhao T, Du J, Zeng H (2020) Interplay between endoplasmic reticulum stress and non-coding RNAs in cancer. J Hematol Oncol 13:163

Article  PubMed  PubMed Central  Google Scholar 

Zhong J, Xie J, Xiao J, Li D, Xu B et al (2019) Inhibition of PDE4 by FCPR16 induces AMPK-dependent autophagy and confers neuroprotection in SH-SY5Y cells

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