Antoniel M, Jones K, Antonucci S, Spolaore B, Fogolari F, Petronilli V, Giorgio V, Carraro M, Di Lisa F, Forte M, Szabo I, Lippe G, Bernardi P (2018) The unique histidine in OSCP subunit of F-ATP synthase mediates inhibition of the permeability transition pore by acidic pH. EMBO Rep 19:257–268. https://doi.org/10.15252/embr.201744705
Article CAS PubMed Google Scholar
Arslan F, Lai RC, Smeets MB, Akeroyd L, Choo A, Aguor EN, Timmers L, van Rijen HV, Doevendans PA, Pasterkamp G, Lim SK, de Kleijn DP (2013) Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury. Stem Cell Res 10:301–312. https://doi.org/10.1016/j.scr.2013.01.002
Article CAS PubMed Google Scholar
Baines CP, Kaiser RA, Purcell NH, Blair NS, Osinska H, Hambleton MA, Brunskill EW, Sayen MR, Gottlieb RA, Dorn GW, Robbins J, Molkentin JD (2005) Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434:658–662. https://doi.org/10.1038/nature03434
Article CAS PubMed Google Scholar
Baines CP, Wang L, Cohen MV, Downey JM (1999) Myocardial protection by insulin is dependent on phospatidylinositol 3-kinase but not protein kinase C or KATP channels in the isolated rabbit heart. Basic Res Cardiol 94:188–198. https://doi.org/10.1007/s003950050142
Article CAS PubMed Google Scholar
Ban K, Cooper AJ, Samuel S, Bhatti A, Patel M, Izumo S, Penninger JM, Backx PH, Oudit GY, Tsushima RG (2008) Phosphatidylinositol 3-kinase gamma is a critical mediator of myocardial ischemic and adenosine-mediated preconditioning. Circ Res 103:643–653. https://doi.org/10.1161/CIRCRESAHA.108.175018
Article CAS PubMed Google Scholar
Basalay MV, Mastitskaya S, Mrochek A, Ackland GL, Del Arroyo AG, Sanchez J, Sjoquist PO, Pernow J, Gourine AV, Gourine A (2016) Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning. Cardiovasc Res 112:669–676. https://doi.org/10.1093/cvr/cvw216
Article CAS PubMed PubMed Central Google Scholar
Baxter GF, Mocanu MM, Brar BK, Latchman DS, Yellon DM (2001) Cardioprotective effects of transforming growth factor-beta1 during early reoxygenation or reperfusion are mediated by p42/p44 MAPK. J Cardiovasc Pharmacol 38:930–939. https://doi.org/10.1097/00005344-200112000-00015
Article CAS PubMed Google Scholar
Beikoghli Kalkhoran S, Kararigas G (2022) Oestrogenic regulation of mitochondrial dynamics. Int J Mol Sci. https://doi.org/10.3390/ijms23031118
Article PubMed PubMed Central Google Scholar
Bell RM, Basalay M, Botker HE, Beikoghli Kalkhoran S, Carr RD, Cunningham J, Davidson SM, England TJ, Giesz S, Ghosh AK, Golforoush P, Gourine AV, Hausenloy DJ, Heusch G, Ibanez B, Kleinbongard P, Lecour S, Lukhna K, Ntsekhe M, Ovize M, Salama AD, Vilahur G, Walker JM, Yellon DM (2022) Remote ischaemic conditioning: defining critical criteria for success-report from the 11th Hatter Cardiovascular Workshop. Basic Res Cardiol 117:39. https://doi.org/10.1007/s00395-022-00947-2
Article CAS PubMed PubMed Central Google Scholar
Bell RM, Yellon DM (2003) Atorvastatin, administered at the onset of reperfusion, and independent of lipid lowering, protects the myocardium by up-regulating a pro-survival pathway. J Am Coll Cardiol 41:508–515. https://doi.org/10.1016/s0735-1097(02)02816-4
Article CAS PubMed Google Scholar
Bell RM, Yellon DM (2003) Bradykinin limits infarction when administered as an adjunct to reperfusion in mouse heart: the role of PI3K, Akt and eNOS. J Mol Cell Cardiol 35:185–193. https://doi.org/10.1016/s0022-2828(02)00310-3
Article CAS PubMed Google Scholar
Bhamra GS, Hausenloy DJ, Davidson SM, Carr RD, Paiva M, Wynne AM, Mocanu MM, Yellon DM (2008) Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening. Basic Res Cardiol 103:274–284. https://doi.org/10.1007/s00395-007-0691-y
Article CAS PubMed Google Scholar
Bonora M, Giorgi C, Pinton P (2022) Molecular mechanisms and consequences of mitochondrial permeability transition. Nat Rev Mol Cell Biol 23:266–285. https://doi.org/10.1038/s41580-021-00433-y
Article CAS PubMed Google Scholar
Botker HE, Cabrera-Fuentes HA, Ruiz-Meana M, Heusch G, Ovize M (2020) Translational issues for mitoprotective agents as adjunct to reperfusion therapy in patients with ST-segment elevation myocardial infarction. J Cell Mol Med 24:2717–2729. https://doi.org/10.1111/jcmm.14953
Article PubMed PubMed Central Google Scholar
Bouwman RA, Salic K, Padding FG, Eringa EC, van Beek-Harmsen BJ, Matsuda T, Baba A, Musters RJ, Paulus WJ, de Lange JJ, Boer C (2006) Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger. Circulation 114:I226-232. https://doi.org/10.1161/CIRCULATIONAHA.105.000570
Article CAS PubMed Google Scholar
Bromage DI, Taferner S, He Z, Ziff OJ, Yellon DM, Davidson SM (2019) Stromal cell-derived factor-1alpha signals via the endothelium to protect the heart against ischaemia-reperfusion injury. J Mol Cell Cardiol 128:187–197. https://doi.org/10.1016/j.yjmcc.2019.02.002
Article CAS PubMed PubMed Central Google Scholar
Busca R, Pouyssegur J, Lenormand P (2016) ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy? Front Cell Dev Biol 4:53. https://doi.org/10.3389/fcell.2016.00053
Article PubMed PubMed Central Google Scholar
Camacho X, Nedkoff L, Wright FL, Nghiem N, Buajitti E, Goldacre R, Rosella LC, Seminog O, Tan EJ, Hayes A, Hayen A, Wilson N, Blakely T, Clarke P (2022) Relative contribution of trends in myocardial infarction event rates and case fatality to declines in mortality: an international comparative study of 1.95 million events in 80.4 million people in four countries. Lancet Public Health 7:e229–e239. https://doi.org/10.1016/S2468-2667(22)00006-8
Chen X, Zhabyeyev P, Azad AK, Wang W, Minerath RA, DesAulniers J, Grueter CE, Murray AG, Kassiri Z, Vanhaesebroeck B, Oudit GY (2019) Endothelial and cardiomyocyte PI3Kbeta divergently regulate cardiac remodelling in response to ischaemic injury. Cardiovasc Res 115:1343–1356. https://doi.org/10.1093/cvr/cvy298
Article CAS PubMed Google Scholar
Crompton M, Costi A (1990) A heart mitochondrial Ca2(+)-dependent pore of possible relevance to re-perfusion-induced injury. Evidence that ADP facilitates pore interconversion between the closed and open states. Biochem J 266:33–39. https://doi.org/10.1042/bj2660033
Article CAS PubMed PubMed Central Google Scholar
Crompton M, Costi A, Hayat L (1987) Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria. Biochem J 245:915–918. https://doi.org/10.1042/bj2450915
Article CAS PubMed PubMed Central Google Scholar
Davidson SM, Adameova A, Barile L, Cabrera-Fuentes HA, Lazou A, Pagliaro P, Stenslokken KO, Garcia-Dorado D, Action E-CC (2020) Mitochondrial and mitochondrial-independent pathways of myocardial cell death during ischaemia and reperfusion injury. J Cell Mol Med 24:3795–3806. https://doi.org/10.1111/jcmm.15127
Article PubMed PubMed Central Google Scholar
Davidson SM, Hausenloy D, Duchen MR, Yellon DM (2006) Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection. Int J Biochem Cell Biol 38:414–419. https://doi.org/10.1016/j.biocel.2005.09.017
Article CAS PubMed Google Scholar
Davidson SM, Yellon DM, Murphy MP, Duchen MR (2012) Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation. Cardiovasc Res 93:445–453. https://doi.org/10.1093/cvr/cvr349
Article CAS PubMed Google Scholar
Diaz-Ruiz JL, Macias-Lopez A, Alcala-Vargas F, Guevara-Chavez JG, Mejia-Uribe A, Silva-Palacios A, Zuniga-Munoz A, Zazueta C, Buelna-Chontal M (2019) Redox signaling in ischemic postconditioning protection involves PKCepsilon and Erk1/2 pathways and converges indirectly in Nrf2 activation. Cell Signal 64:109417. https://doi.org/10.1016/j.cellsig.2019.109417
Article CAS PubMed Google Scholar
Ferdinandy P, Andreadou I, Baxter GF, Botker HE, Davidson SM, Dobrev D, Gersh BJ, Heusch G, Lecour S, Ruiz-Meana M, Zuurbier CJ, Hausenloy DJ, Schulz R (2023) Interaction of cardiovascular nonmodifiable risk factors, comorbidities and comedications with ischemia/reperfusion injury and cardioprotection by pharmacological treatments and ischemic conditioning. Pharmacol Rev 75:159–216. https://doi.org/10.1124/pharmrev.121.000348
Article PubMed PubMed Central Google Scholar
Fryer RM, Pratt PF, Hsu AK, Gross GJ (2001) Differential activation of extracellular signal regulated kinase isoforms in preconditioning and opioid-induced cardioprotection. J Pharmacol Exp Ther 296:642–649
Gao J, Chang Chua C, Chen Z, Wang H, Xu X, Hamdy RC, McMullen JR, Shioi T, Izumo S, Chua BH (2007) Resistin, an adipocytokine, offers protection against acute myocardial infarction. J Mol Cell Cardiol 43:601–609. https://doi.org/10.1016/j.yjmcc.2007.08.009
Article CAS PubMed PubMed Central Google Scholar
Ghigo A, Laffargue M, Li M, Hirsch E (2017) PI3K and calcium signaling in cardiovascular disease. Circ Res 121:282–292. https://doi.org/10.1161/CIRCRESAHA.117.310183
Article CAS PubMed Google Scholar
Granata R, Trovato L, Gallo MP, Destefanis S, Settanni F, Scarlatti F, Brero A, Ramella R, Volante M, Isgaard J, Levi R, Papotti M, Alloatti G, Ghigo E (2009) Growth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heart. Cardiovasc Res 83:303–312. https://doi.org/10.1093/cvr/cvp090
Article CAS PubMed Google Scholar
Griffiths EJ, Halestrap AP (1995) Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. Biochem J 307(Pt 1):93–98. https://doi.org/10.1042/bj3070093
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